Searchable abstracts of presentations at key conferences on reproductive biology and medicine

ra0001p179 | (1) | WCRB2014

Krüppel-like factor 6 (klf6) is expressed in rat pituitary stem/progenitor cells and regulates the PRRX2 gene

Ueharu Hiroki , Higuchi Masashi , Nishimura Naoto , Yoshida Saishu , Nishihara Hiroto , Kato Takako , Kato Yukio

Introduction: Paired-related transcription factors, PRRX1 and PRRX2, which are expressed in mesenchymal tissues and participate in mesenchymal cell differentiation, were recently found in stem/progenitor cells of the pituitary gland of ectodermal origin. The present study aimed to clarify the role of PRRX1 and PRRX2 in the pituitary gland by identifying factors that regulate the expression of both genes.Materials and methods: Immunohistochemistry, promot...